INT329081

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Context Info
Confidence 0.12
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.68
Pain Relevance 0.76

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Stard4) transport (Stard4) mitochondrion (Stard4)
Anatomy Link Frequency
finger 1
Stard4 (Mus musculus)
Pain Link Frequency Relevance Heat
Multiple sclerosis 123 99.72 Very High Very High Very High
Inflammation 3 5.00 Very Low Very Low Very Low
Demyelination 3 5.00 Very Low Very Low Very Low
intrathecal 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
glial activation 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Demyelinating Disease 126 99.72 Very High Very High Very High
Disorder Of Lipid Metabolism 9 84.84 Quite High
Disease 20 5.00 Very Low Very Low Very Low
INFLAMMATION 4 5.00 Very Low Very Low Very Low
Recurrence 3 5.00 Very Low Very Low Very Low
Neurological Disease 2 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 2 5.00 Very Low Very Low Very Low
Rupture 2 5.00 Very Low Very Low Very Low
Disease Progression 2 5.00 Very Low Very Low Very Low
Coronary Artery Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Additional proteins with low p-values in the comparisons of both MScl types with the controls include StAR-related lipid transfer protein 4 (2.551 fold increase in PP MScl compared to controls and 2.837 fold increase in RR MScl compared to controls), LON peptidase N-terminal domain and RING finger protein (2.847 fold increase in PP MScl and 2.212 fold increase in RR MScl), and ryanodine receptor 1 (2.129 fold increase in PP MScl and 1.877 fold increase in RR MScl).


Positive_regulation (increase) of StAR-related lipid transfer protein 4 in finger associated with multiple sclerosis
1) Confidence 0.12 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2929207 Disease Relevance 1.68 Pain Relevance 0.76

General Comments

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