INT329084

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Context Info
Confidence 0.12
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.63
Pain Relevance 0.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Gc) transport (Gc) extracellular space (Gc)
extracellular region (Gc)
Anatomy Link Frequency
thyroid 2
Gc (Mus musculus)
Pain Link Frequency Relevance Heat
Multiple sclerosis 123 99.16 Very High Very High Very High
Demyelination 3 38.16 Quite Low
Inflammation 3 5.00 Very Low Very Low Very Low
intrathecal 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
glial activation 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Demyelinating Disease 126 99.16 Very High Very High Very High
Neurological Disease 2 97.88 Very High Very High Very High
Disease 21 83.76 Quite High
Apoptosis 78 80.32 Quite High
Autoimmune Disease 1 57.52 Quite High
Targeted Disruption 29 52.12 Quite High
Death 8 43.20 Quite Low
Huntington's Chorea 1 42.96 Quite Low
Injury 2 39.96 Quite Low
Necrosis 4 35.36 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Recently, a CSF proteomics study showed that serum levels of vitamin D-binding protein were decreased significantly in RR MScl patients compared to other neurological disorders[35].
Negative_regulation (decreased) of Gene_expression (levels) of vitamin D-binding protein associated with multiple sclerosis and neurological disease
1) Confidence 0.12 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2929207 Disease Relevance 1.20 Pain Relevance 0.45
No exogenous nuclear ligand is needed because Hr is capable of repressing gene expression of unliganded Vitamin D [15], [38] and thyroid receptors [39].
Negative_regulation (repressing) of Gene_expression (expression) of Vitamin D in thyroid
2) Confidence 0.02 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2944824 Disease Relevance 0.43 Pain Relevance 0

General Comments

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