INT329158

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Context Info
Confidence 0.49
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.30
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CNTNAP2) cell adhesion (CNTNAP2) Golgi apparatus (CNTNAP2)
enzyme binding (CNTNAP2)
CNTNAP2 (Homo sapiens)
Pain Link Frequency Relevance Heat
potassium channel 83 97.18 Very High Very High Very High
Neuropathic pain 2 70.44 Quite High
Hippocampus 7 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Sciatic nerve 4 5.00 Very Low Very Low Very Low
hyperexcitability 2 5.00 Very Low Very Low Very Low
Pyramidal cell 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 19 99.60 Very High Very High Very High
Thymoma 7 98.54 Very High Very High Very High
Syndrome 44 97.00 Very High Very High Very High
Isaacs Syndrome 25 93.04 High High
Autism 1 85.48 High High
Epilepsy 16 85.04 High High
Schizophrenia 1 84.64 Quite High
Cognitive Disorder 2 79.52 Quite High
Sleep Disorders 8 72.96 Quite High
Neuropathic Pain 2 70.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although in this cohort, only three of the five patients with Morvan’s syndrome had Caspr2-antibodies, in a further nine patients with Morvan’s syndrome and VGKC-antibodies, the majority had Caspr2-antibodies and six had thymomas (Vincent, 2009 and unpublished observations); it will be interesting to look for Caspr2 expression in these tumours.
Positive_regulation (look) of Gene_expression (expression) of Caspr2 associated with cancer, syndrome, thymoma and potassium channel
1) Confidence 0.49 Published 2010 Journal Brain Section Body Doc Link PMC2929337 Disease Relevance 1.30 Pain Relevance 0.26

General Comments

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