INT329265

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Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.04
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Ptk2, Wnt2) extracellular matrix organization (Ptk2) cell-cell signaling (Wnt2)
microtubule organizing center (Ptk2) signal transducer activity (Ptk2) cytosol (Ptk2)
Ptk2 (Rattus norvegicus)
Wnt2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
depression 2 69.76 Quite High
Dopamine 4 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 6 100.00 Very High Very High Very High
Toxicity 84 99.36 Very High Very High Very High
Cancer 6 71.48 Quite High
Depression 2 69.76 Quite High
Pancreatic Cancer 6 26.08 Quite Low
Apoptosis 2 7.28 Low Low
Reprotox - General 1 8 5.00 Very Low Very Low Very Low
Disease 6 5.00 Very Low Very Low Very Low
Stress 4 5.00 Very Low Very Low Very Low
Renal Disease 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Figure 8A shows how a possible interaction between the Wnt signalling pathway, Regulation of Actin Cytoskeleton (linked to PCFs) and Focal Adhesion (predictive of toxicity outcome) could lead to a perturbation of actin cytoskeleton polymerization.
Focal Adhesion Binding (interaction) of Wnt associated with toxicity and adhesions
1) Confidence 0.05 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2929951 Disease Relevance 0.52 Pain Relevance 0.03
Figure 8A shows how a possible interaction between the Wnt signalling pathway, Regulation of Actin Cytoskeleton (linked to PCFs) and Focal Adhesion (predictive of toxicity outcome) could lead to a perturbation of actin cytoskeleton polymerization.
Focal Adhesion Binding (interaction) of Wnt associated with toxicity and adhesions
2) Confidence 0.05 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2929951 Disease Relevance 0.52 Pain Relevance 0.03

General Comments

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