INT329278

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Context Info
Confidence 0.22
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.82

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Fos) nucleolus (Fos) nucleus (Fos)
DNA binding (Fos) transcription factor binding (Fos) response to stress (Fos)
Anatomy Link Frequency
nucleus accumbens 2
posterior 2
Vta1 (Rattus norvegicus)
Fos (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Ventral tegmentum 52 100.00 Very High Very High Very High
Nucleus accumbens 4 98.16 Very High Very High Very High
Raphe 20 79.92 Quite High
midbrain 2 70.20 Quite High
agonist 6 62.56 Quite High
Morphine 4 58.20 Quite High
Eae 16 56.08 Quite High
nMDA receptor antagonist 2 54.32 Quite High
cocaine 2 52.92 Quite High
antagonist 16 50.00 Quite Low
Disease Link Frequency Relevance Heat
Drug Dependence 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We mentioned in the background section that carbachol administration into the posterior VTA increases c-Fos expression in the SuM.
VTA Positive_regulation (increases) of Gene_expression (expression) of c-Fos in posterior associated with ventral tegmentum
1) Confidence 0.22 Published 2010 Journal BMC Neurosci Section Body Doc Link PMC2930627 Disease Relevance 0 Pain Relevance 0.39
The posterior but not anterolateral VTA had reliable increases in c-Fos expression after intra-SuM picrotoxin, while the medial nucleus accumbens shell had more reliable increases in c-Fos counts than the accumbens core (Figure 5B; Table 1).
VTA Positive_regulation (increases) of Gene_expression (expression) of c-Fos in nucleus accumbens associated with nucleus accumbens and ventral tegmentum
2) Confidence 0.22 Published 2010 Journal BMC Neurosci Section Body Doc Link PMC2930627 Disease Relevance 0 Pain Relevance 0.43

General Comments

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