INT329289

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Context Info
Confidence 0.44
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.94
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Cd226)
Cd226 (Mus musculus)
Pain Link Frequency Relevance Heat
chemokine 6 100.00 Very High Very High Very High
rheumatoid arthritis 28 84.40 Quite High
antagonist 2 66.56 Quite High
Inflammatory response 2 61.56 Quite High
cytokine 45 37.44 Quite Low
Inflammation 26 5.00 Very Low Very Low Very Low
Infliximab 3 5.00 Very Low Very Low Very Low
fibrosis 3 5.00 Very Low Very Low Very Low
Etanercept 3 5.00 Very Low Very Low Very Low
tolerance 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Asthma 104 98.96 Very High Very High Very High
Hypersensitivity 24 90.72 High High
Rheumatoid Arthritis 29 84.40 Quite High
Disease 21 82.16 Quite High
INFLAMMATION 28 61.20 Quite High
Targeted Disruption 6 52.68 Quite High
Necrosis 4 50.00 Quite Low
Cancer 4 50.00 Quite Low
Eosinophilia 8 5.00 Very Low Very Low Very Low
Airway Remodeling 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
On the one hand, Sen et al. figured out that the bronchial mucosa of asthmatic patients reveal massive accumulation of iNKT cells expressing the chemokine receptor CCR9 and CD226 in large amounts.
Gene_expression (expressing) of CD226 associated with asthma and chemokine
1) Confidence 0.44 Published 2010 Journal Journal of Allergy Section Body Doc Link PMC2957587 Disease Relevance 0.74 Pain Relevance 0.05
A limitation of the current investigation is that no correction for multiple testing was applied and, if it was applied, the associations with change in DAS28 would not remain statistically significant (AFF3, pc=0.195; CD226, pc=0.624).
Neg (not) Gene_expression (significant) of CD226
2) Confidence 0.41 Published 2010 Journal Annals of the Rheumatic Diseases Section Body Doc Link PMC2930850 Disease Relevance 0.21 Pain Relevance 0.11

General Comments

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