INT329290

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Context Info
Confidence 0.22
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.46
Pain Relevance 0.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Cd226)
Cd226 (Mus musculus)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 28 96.64 Very High Very High Very High
chemokine 6 95.36 Very High Very High Very High
Adalimumab 2 79.92 Quite High
Infliximab 3 79.36 Quite High
Etanercept 3 78.88 Quite High
cytokine 45 31.84 Quite Low
Inflammation 26 5.00 Very Low Very Low Very Low
fibrosis 3 5.00 Very Low Very Low Very Low
tolerance 3 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 29 96.64 Very High Very High Very High
Asthma 104 92.32 High High
Hypersensitivity 24 85.12 High High
Disease 21 84.24 Quite High
Necrosis 4 75.00 Quite High
Cancer 4 75.00 Quite High
Targeted Disruption 6 47.08 Quite Low
INFLAMMATION 28 5.00 Very Low Very Low Very Low
Eosinophilia 8 5.00 Very Low Very Low Very Low
Airway Remodeling 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the combined analysis, SNPs mapping to AFF3 and CD226 had a statistically significant association with the response to anti-TNF treatment under an additive model.
CD226 Binding (association) of
1) Confidence 0.22 Published 2010 Journal Annals of the Rheumatic Diseases Section Abstract Doc Link PMC2930850 Disease Relevance 0.84 Pain Relevance 0.34
Additionally, these cells are capable of inducing a strong TH2 bias upon CD226 engagement [189].
CD226 Binding (engagement) of
2) Confidence 0.20 Published 2010 Journal Journal of Allergy Section Body Doc Link PMC2957587 Disease Relevance 0.62 Pain Relevance 0.05

General Comments

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