INT329452

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.23
Pain Relevance 1.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Tac1, Oprd1) extracellular space (Tac1) extracellular region (Tac1)
cytoplasm (Oprd1) signal transducer activity (Oprd1)
Tac1 (Mus musculus)
Oprd1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
substance P 10 100.00 Very High Very High Very High
opioid receptor 1 100.00 Very High Very High Very High
antagonist 22 96.92 Very High Very High Very High
Opioid 9 96.48 Very High Very High Very High
opiate 2 93.64 High High
addiction 6 91.64 High High
tolerance 1 90.36 High High
amygdala 4 86.00 High High
Endogenous opioid 3 85.00 Quite High
Nucleus accumbens 2 83.76 Quite High
Disease Link Frequency Relevance Heat
Targeted Disruption 4 79.36 Quite High
Obesity 6 75.48 Quite High
Drug Dependence 1 45.72 Quite Low
Body Weight 2 25.48 Quite Low
Functional Bowel Disorder 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Vomiting 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Recently it has been suggested that the neurokinin 1 (NK1)-receptor system, and its endogenous ligand substance P (SP), interacts with the opioid receptor systems to regulate reward related behaviors.
NK1 Binding (interacts) of opioid receptor associated with opioid receptor and substance p
1) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2931709 Disease Relevance 0.23 Pain Relevance 1.40

General Comments

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