INT329472

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.26
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (IRF6, Ca2) cytoplasm (IRF6, Ca2) extracellular space (Ca2)
lyase activity (Ca2) nucleus (IRF6) DNA binding (IRF6)
Anatomy Link Frequency
endothelial cells 1
IRF6 (Homo sapiens)
Ca2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 8 5.00 Very Low Very Low Very Low
Cannabinoid receptor 2 5.00 Very Low Very Low Very Low
member 8 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
Endocannabinoid 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Increased Venous Pressure Under Development 1 98.00 Very High Very High Very High
Hypertension 1 83.08 Quite High
Atherosclerosis 1 81.44 Quite High
Targeted Disruption 5 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
One of the less examined LPs is lysophosphatidylinositol (LPI), a glycerol-based LP that has recently been reported to specifically interact with the G-protein-coupled receptor 55 (GPR55) (Oka et al., 2007; Waldeck-Weiermair et al., 2008) that mediates a transient Ca2+ increase upon stimulation of endothelial cells with LPI (Henstridge et al., 2008; Lauckner et al., 2008; Waldeck-Weiermair et al., 2008).
LPs Binding (interact) of Ca2 in endothelial cells
1) Confidence 0.00 Published 2010 Journal British Journal of Pharmacology Section Body Doc Link PMC2931756 Disease Relevance 0.26 Pain Relevance 0

General Comments

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