INT329479

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Context Info
Confidence 0.04
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.71
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (TNFRSF11B, TNF) extracellular region (TNFRSF11B, TNF) extracellular matrix organization (TNFRSF11B, TNF)
extracellular space (TNF) proteinaceous extracellular matrix (TNFRSF11B) plasma membrane (TNF)
TNFRSF11B (Homo sapiens)
TNF (Homo sapiens)
Pain Link Frequency Relevance Heat
cva 11 5.00 Very Low Very Low Very Low
Potency 3 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
Bioavailability 2 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
transdermal 1 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
Paracetamol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypercalcemia 22 97.32 Very High Very High Very High
Apoptosis 2 95.40 Very High Very High Very High
Necrosis 1 78.64 Quite High
Cancer 2 78.28 Quite High
Osteoporosis 80 69.04 Quite High
Disorders Of Creatine Metabolism 2 60.52 Quite High
Renal Failure 1 59.20 Quite High
Alopecia 1 53.24 Quite High
Postmenopausal Osteoporosis 13 50.00 Quite Low
Syndrome 5 45.08 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, because OPG also binds to the cytotoxic ligand TRAIL and other members of the TNF family, a specific fully human antibody against RANKL has been developed (Amgen).
OPG Binding (binds) of TNF
1) Confidence 0.04 Published 2010 Journal Osteoporos Int Section Body Doc Link PMC2931762 Disease Relevance 0.71 Pain Relevance 0

General Comments

This test has worked.

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