INT329549

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Context Info
Confidence 0.25
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.23
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (PPARA, ESRRA) nucleus (PPARA, ESRRA) DNA binding (PPARA, ESRRA)
lipid binding (PPARA) small molecule metabolic process (PPARA) lipid metabolic process (PPARA)
PPARA (Homo sapiens)
ESRRA (Homo sapiens)
Pain Link Frequency Relevance Heat
ischemia 11 83.52 Quite High
Angina 2 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 48 91.20 High High
Cv Unclassified Under Development 7 83.52 Quite High
Coronary Artery Disease 4 46.56 Quite Low
Syndrome 15 29.20 Quite Low
Disease 4 5.00 Very Low Very Low Very Low
Heart Disease 2 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Obesity 2 5.00 Very Low Very Low Very Low
Cv General 3 Under Development 2 5.00 Very Low Very Low Very Low
Myocardial Infarction 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These studies demonstrate that the variant PPARA promoter sequence exhibits diminished ERR binding and decreased ERR-mediated transcriptional activation, compared to the wild-type PPARA ?
PPARA Negative_regulation (diminished) of ERR Binding (binding) of
1) Confidence 0.25 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2933242 Disease Relevance 0.23 Pain Relevance 0.04

General Comments

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