INT329677

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Context Info
Confidence 0.31
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.23
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (CDKN2A, CBX7) nucleoplasm (CDKN2A) DNA binding (CDKN2A)
protein complex (CDKN2A) cytoplasm (CDKN2A) cytosol (CDKN2A)
CDKN2A (Homo sapiens)
CBX7 (Homo sapiens)
Pain Link Frequency Relevance Heat
palliative 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Lifespan 8 98.28 Very High Very High Very High
Metastasis 36 92.64 High High
Cancer 62 92.20 High High
Stomach Cancer 108 91.52 High High
Aging 36 56.00 Quite High
Hyperplasia 6 5.00 Very Low Very Low Very Low
Lymphatic System Cancer 4 5.00 Very Low Very Low Very Low
Colon Cancer 4 5.00 Very Low Very Low Very Low
Alagille Syndrome 2 5.00 Very Low Very Low Very Low
Adenocarcinoma 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To determine the possible mechanisms of CBX7 in gastric carcinogenesis, we studied the relationship between CBX7 and p16(INK4a), which is a down-stream target of CBX7 during its controlling human normal cells lifespan.
p16 Regulation (target) of CBX7 associated with lifespan
1) Confidence 0.31 Published 2010 Journal J Exp Clin Cancer Res Section Body Doc Link PMC2933612 Disease Relevance 1.12 Pain Relevance 0
To determine the possible mechanisms of CBX7 in gastric carcinogenesis, we studied the relationship between CBX7 and p16(INK4a), which is a down-stream target of CBX7 during its controlling human normal cells lifespan.
INK4a Regulation (target) of CBX7 associated with lifespan
2) Confidence 0.27 Published 2010 Journal J Exp Clin Cancer Res Section Body Doc Link PMC2933612 Disease Relevance 1.12 Pain Relevance 0

General Comments

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