INT329679

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Context Info
Confidence 0.31
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 4.18
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (CBX7, CDKN2A) nucleoplasm (CDKN2A) DNA binding (CDKN2A)
protein complex (CDKN2A) cytoplasm (CDKN2A) cytosol (CDKN2A)
CBX7 (Homo sapiens)
CDKN2A (Homo sapiens)
Pain Link Frequency Relevance Heat
palliative 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aging 72 100.00 Very High Very High Very High
Cancer 124 98.56 Very High Very High Very High
Stomach Cancer 216 96.00 Very High Very High Very High
Hyperplasia 12 89.44 High High
Colon Cancer 8 84.48 Quite High
Lifespan 16 69.44 Quite High
Metastasis 72 63.04 Quite High
Lymphatic System Cancer 8 5.00 Very Low Very Low Very Low
Alagille Syndrome 4 5.00 Very Low Very Low Very Low
Adenocarcinoma 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It's already known that CBX7 regulates cellular senescence and proliferation via Ink4a/Arf locus, which encodes the cyclin-dependent kinase inhibitor p16(INK4a) and tumor suppressor p19(Arf) [20].
CBX7 Regulation (regulates) of Ink4a associated with aging and cancer
1) Confidence 0.31 Published 2010 Journal J Exp Clin Cancer Res Section Body Doc Link PMC2933612 Disease Relevance 0.89 Pain Relevance 0
Regulation of INK4a/ARF locus by CBX7 also needs further confirmation in cancer cells.
CBX7 Regulation (Regulation) of INK4a associated with cancer
2) Confidence 0.31 Published 2010 Journal J Exp Clin Cancer Res Section Body Doc Link PMC2933612 Disease Relevance 1.20 Pain Relevance 0
It's already known that CBX7 regulates cellular senescence and proliferation via Ink4a/Arf locus, which encodes the cyclin-dependent kinase inhibitor p16(INK4a) and tumor suppressor p19(Arf) [20].
CBX7 Regulation (regulates) of Arf associated with aging and cancer
3) Confidence 0.30 Published 2010 Journal J Exp Clin Cancer Res Section Body Doc Link PMC2933612 Disease Relevance 0.89 Pain Relevance 0
Regulation of INK4a/ARF locus by CBX7 also needs further confirmation in cancer cells.
CBX7 Regulation (Regulation) of ARF associated with cancer
4) Confidence 0.30 Published 2010 Journal J Exp Clin Cancer Res Section Body Doc Link PMC2933612 Disease Relevance 1.20 Pain Relevance 0

General Comments

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