INT329718

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Context Info
Confidence 0.09
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.54
Pain Relevance 0.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Cd28)
Anatomy Link Frequency
T lymphocytes 1
Cd28 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammatory response 30 90.80 High High
Inflammation 69 82.48 Quite High
cytokine 18 60.32 Quite High
antagonist 6 23.24 Low Low
palliative 3 5.00 Very Low Very Low Very Low
aspirin 3 5.00 Very Low Very Low Very Low
cINOD 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Influenza Virus Infection 6 94.60 High High
INFLAMMATION 102 90.44 High High
Infection 30 85.16 High High
Aging 18 68.12 Quite High
Disease 21 64.16 Quite High
Endotoxemia 3 31.16 Quite Low
Urinary Tract Infection 3 20.00 Low Low
Communicable Diseases 57 8.80 Low Low
Convalescence 51 5.00 Very Low Very Low Very Low
Stress 48 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In this work, we observed a decreased abundance of CD28, CD69 and LCK mRNA in acutely infected aged patients, compared to healthy aged.
Transcription (abundance) of CD28
1) Confidence 0.09 Published 2010 Journal Immun Ageing Section Body Doc Link PMC2933667 Disease Relevance 0.74 Pain Relevance 0.35
Decreased abundance of CD28 and LCK mRNA indicates that early signaling events following antigen stimulation are altered in T lymphocytes.
Transcription (abundance) of CD28 in T lymphocytes
2) Confidence 0.09 Published 2010 Journal Immun Ageing Section Body Doc Link PMC2933667 Disease Relevance 0.16 Pain Relevance 0
The comparison of the levels of CD28, CD69 and LCK transcripts between healthy aged and healthy young probands previously showed a respective 38%, 30% and 23% decrease in the aged probands [13].
Transcription (levels) of CD28
3) Confidence 0.07 Published 2010 Journal Immun Ageing Section Body Doc Link PMC2933667 Disease Relevance 0.64 Pain Relevance 0.28

General Comments

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