INT329783

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Context Info
Confidence 0.26
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.82
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CHEK1) nucleoplasm (CHEK1) cytoskeleton (CHEK1)
nucleus (CHEK1) cell cycle (CHEK1) cytoplasm (CHEK1)
CHEK1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 1 12.72 Low Low
metalloproteinase 14 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 102 99.44 Very High Very High Very High
Neuroblastoma 1 99.30 Very High Very High Very High
Reprotox - General 1 58 93.28 High High
Breast Cancer 22 92.28 High High
Metastasis 43 79.04 Quite High
Apoptosis 21 44.24 Quite Low
Hyperplasia 4 41.36 Quite Low
Death 6 35.52 Quite Low
Hypoxia 1 17.28 Low Low
Infection 1 10.64 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In ovarian and neuroblastoma cancer cells, genistein activates Chk1 and Chk2, which in turn activate, or dephosphorylate, Cdc25C and Cdc25A [56, 58].
Phosphorylation (dephosphorylate) of Chk1 associated with neuroblastoma and cancer
1) Confidence 0.26 Published 2010 Journal Cancer Metastasis Rev Section Body Doc Link PMC2933845 Disease Relevance 0.82 Pain Relevance 0

General Comments

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