INT329787

Context Info Confidence 0.08 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 1.21 Pain Relevance 0.03

nucleoplasm (CCNB1) protein complex assembly (CCNB1) cytoplasm (CCNB1) cytosol (CCNB1) nucleus (CCNB1) cytoskeleton (CCNB1)

CCNB1 (Homo sapiens)

Pain Link Frequency Relevance Heat cytokine 1 54.80 metalloproteinase 14 5.00 chemokine 1 5.00 Pain 1 5.00

Disease Link Frequency Relevance Heat Cancer 102 97.52 Breast Cancer 22 95.68 Apoptosis 21 86.32 Hyperplasia 4 83.44 Death 6 77.60 Neuroblastoma 1 76.84 Reprotox - General 1 58 71.52 Hypoxia 1 59.36 Metastasis 43 57.28 Infection 1 52.72

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

These combined effects of genistein on Cdc2, cyclin B1, as well as other cell cycle proteins, all serve to decrease cancer cell proliferation and therefore represent potential therapeutic targets.

Regulation (effects) of cyclin B1 associated with cancer

1) Confidence 0.08 Published 2010 Journal Cancer Metastasis Rev Section Body Doc Link PMC2933845 Disease Relevance 1.21 Pain Relevance 0.03

General Comments

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