INT32980

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Context Info
Confidence 0.45
First Reported 1985
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0
Pain Relevance 1.98

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (OPRM1) endoplasmic reticulum (OPRM1) plasma membrane (OPRM1)
signal transducer activity (OPRM1)
OPRM1 (Homo sapiens)
Pain Link Frequency Relevance Heat
opioid receptor 11 100.00 Very High Very High Very High
opiate 4 100.00 Very High Very High Very High
agonist 3 99.98 Very High Very High Very High
Immobilon 2 99.68 Very High Very High Very High
Enkephalin 6 99.16 Very High Very High Very High
antagonist 2 95.36 Very High Very High Very High
Glutamate receptor 3 75.00 Quite High
MU agonist 1 70.76 Quite High
tolerance 1 64.20 Quite High
analgesia 1 63.64 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Chronic ethanol induces changes in opiate receptor function and in met-enkephalin release.
Positive_regulation (induces) of Regulation (changes) of opiate receptor associated with enkephalin, opiate and immobilon
1) Confidence 0.45 Published 1985 Journal Alcohol Section Title Doc Link 2990502 Disease Relevance 0 Pain Relevance 0.96
These findings indicate that an allosteric modulation of mGluR5 can affect the agonist-induced MOR signalling and regulation.
Positive_regulation (induced) of Regulation (regulation) of MOR associated with agonist and opioid receptor
2) Confidence 0.37 Published 2009 Journal Neuropharmacology Section Abstract Doc Link 19162047 Disease Relevance 0 Pain Relevance 1.02

General Comments

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