INT329839

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Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.28
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Tnfsf13b, Ighm) extracellular region (Tnfsf13b) plasma membrane (Tnfsf13b)
Tnfsf13b (Mus musculus)
Ighm (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 30 60.56 Quite High
cytokine 110 50.00 Quite Low
fibrosis 6 44.56 Quite Low
tolerance 20 5.00 Very Low Very Low Very Low
rheumatoid arthritis 16 5.00 Very Low Very Low Very Low
antagonist 14 5.00 Very Low Very Low Very Low
cINOD 4 5.00 Very Low Very Low Very Low
Bioavailability 4 5.00 Very Low Very Low Very Low
chemokine 4 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Autoimmune Disease 50 98.00 Very High Very High Very High
Renal Disease 62 95.20 Very High Very High Very High
Proteinuria 18 91.40 High High
Disease 68 91.20 High High
Hypergammaglobulinemia 4 73.36 Quite High
INFLAMMATION 34 60.56 Quite High
Systemic Lupus Erythematosus 238 54.92 Quite High
Internal Fibrosis 4 45.04 Quite Low
Hyperplasia 6 20.44 Low Low
Syndrome 14 6.60 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
BLyS blockade has little effect on IgG levels in normal mice, but reverses the production of spontaneously produced IgM and IgG autoantibodies in setting of established autoimmunity.
Negative_regulation (blockade) of BLyS Negative_regulation (reverses) of Gene_expression (production) of IgM associated with autoimmune disease
1) Confidence 0.05 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2933908 Disease Relevance 1.14 Pain Relevance 0.03
BLyS blockade has little effect on IgG levels in normal mice, but reverses the production of spontaneously produced IgM and IgG autoantibodies in setting of established autoimmunity.
Negative_regulation (blockade) of BLyS Negative_regulation (reverses) of Gene_expression (produced) of IgM associated with autoimmune disease
2) Confidence 0.05 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2933908 Disease Relevance 1.14 Pain Relevance 0.03

General Comments

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