INT329881

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Context Info
Confidence 0.57
First Reported 2010
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 4.49
Pain Relevance 0.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Ucp2) mitochondrion (Ucp2)
Anatomy Link Frequency
skeletal muscle 2
Ucp2 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory response 12 82.68 Quite High
Inflammation 22 65.32 Quite High
agonist 52 5.00 Very Low Very Low Very Low
Bile 32 5.00 Very Low Very Low Very Low
tolerance 14 5.00 Very Low Very Low Very Low
Spinal cord 4 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Paracetamol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 23 98.96 Very High Very High Very High
Stress 39 96.60 Very High Very High Very High
Hepatotoxicity 8 93.52 High High
Body Weight 6 86.60 High High
INFLAMMATION 30 82.32 Quite High
Insulin Resistance 15 76.88 Quite High
Hepatocellular Cancer 1 70.44 Quite High
Cancer 20 67.20 Quite High
Cardiovascular Disease 4 66.76 Quite High
Cirrhosis 4 65.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Stimulated mRNA expression of uncoupling protein 2 (Ucp2) by PPAR?
Positive_regulation (Stimulated) of Transcription (expression) of Ucp2
1) Confidence 0.57 Published 2010 Journal PPAR Research Section Body Doc Link PMC2933910 Disease Relevance 0.97 Pain Relevance 0.10
Stimulated mRNA expression of uncoupling protein 2 (Ucp2) by PPAR?
Positive_regulation (by) of Transcription (expression) of uncoupling protein 2
2) Confidence 0.41 Published 2010 Journal PPAR Research Section Body Doc Link PMC2933910 Disease Relevance 0.96 Pain Relevance 0.10
Stimulated mRNA expression of uncoupling protein 2 (Ucp2) by PPAR?
Positive_regulation (Stimulated) of Transcription (expression) of Ucp2
3) Confidence 0.41 Published 2010 Journal PPAR Research Section Body Doc Link PMC2933910 Disease Relevance 0.97 Pain Relevance 0.10
Stimulated mRNA expression of uncoupling protein 2 (Ucp2) by PPAR?
Positive_regulation (Stimulated) of Transcription (expression) of uncoupling protein 2
4) Confidence 0.41 Published 2010 Journal PPAR Research Section Body Doc Link PMC2933910 Disease Relevance 0.96 Pain Relevance 0.10
In skeletal muscle, the expression of UCP2 mRNA was significantly increased by berberine [10].
Positive_regulation (increased) of Transcription (expression) of UCP2 in skeletal muscle
5) Confidence 0.38 Published 2011 Journal Evidence-based Complementary and Alternative Medicine : eCAM Section Body Doc Link PMC2952334 Disease Relevance 0.63 Pain Relevance 0
RT–PCR analysis comparing Srebp-1c, Ppard, Ppara, Ins (proinsulin), Ucp-2, Ampk and Gck mRNA expression in BRIN-BD11 cells treated in the absence or presence of increasing concentrations of AA for 24 h was performed.
Positive_regulation (comparing) of Transcription (expression) of Ucp-2
6) Confidence 0.19 Published 2010 Journal Clinical Science (London, England : 1979) Section Body Doc Link PMC2990202 Disease Relevance 0 Pain Relevance 0

General Comments

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