INT329944

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Context Info
Confidence 0.30
First Reported 2011
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.18
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Trpc5) transmembrane transport (Trpc5)
Anatomy Link Frequency
neurite 2
Trpc5 (Mus musculus)
Pain Link Frequency Relevance Heat
Neuronal excitability 2 5.00 Very Low Very Low Very Low
member 8 2 5.00 Very Low Very Low Very Low
Glutamate 2 5.00 Very Low Very Low Very Low
Calcium channel 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Skin Cancer 2 62.68 Quite High
Cancer 2 59.12 Quite High
Disease 8 5.00 Very Low Very Low Very Low
Alzheimer's Dementia 4 5.00 Very Low Very Low Very Low
Neuroblastoma 2 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 2 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Amnesia 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A decrease in the expression of TRPC5 by AICD overexpression might affect neurite outgrowth.

4.

Negative_regulation (decrease) of Gene_expression (expression) of TRPC5 in neurite
1) Confidence 0.30 Published 2011 Journal International Journal of Alzheimer's Disease Section Body Doc Link PMC2935165 Disease Relevance 0.12 Pain Relevance 0
About 2-fold increase and 3-fold decrease in the expressions of PTCH1 and TRPC5, respectively, was observed upon AICD overexpression (Figure 1(a)).
Negative_regulation (decrease) of Gene_expression (expressions) of TRPC5
2) Confidence 0.30 Published 2011 Journal International Journal of Alzheimer's Disease Section Body Doc Link PMC2935165 Disease Relevance 0.06 Pain Relevance 0

General Comments

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