INT329954

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Context Info
Confidence 0.07
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.65
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (PRKCQ, SNRNP70) nucleoplasm (SNRNP70) aging (PRKCQ)
intracellular (PRKCQ) cytoplasm (PRKCQ) cytosol (PRKCQ)
PRKCQ (Homo sapiens)
SNRNP70 (Homo sapiens)
Pain Link Frequency Relevance Heat
Arthritis 76 99.76 Very High Very High Very High
rheumatoid arthritis 39 93.56 High High
Multiple sclerosis 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Crohn's disease 2 5.00 Very Low Very Low Very Low
spinal inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Juvenile Chronic Polyarthritis 72 99.76 Very High Very High Very High
Rheumatoid Arthritis 39 93.56 High High
Disease Susceptibility 2 50.00 Quite Low
Disease 14 21.92 Low Low
Autoimmune Disease 11 5.00 Very Low Very Low Very Low
Arthritis 5 5.00 Very Low Very Low Very Low
Demyelinating Disease 2 5.00 Very Low Very Low Very Low
Diabetes Mellitus 2 5.00 Very Low Very Low Very Low
Low Back Pain 1 5.00 Very Low Very Low Very Low
Rheumatic Diseases 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Both the KIF5A SNP, rs1678542 and the SNP, rs4750316, close to PRKCQ, showed weak protective association with JIA (allelic OR=0.91, 95% CI 0.82 to 1.01, trend p=0.08 and allelic OR=0.88, 95% CI 0.77 to 1.0, trend p=0.05, respectively), although the evidence for association did not reach the corrected threshold for any of these loci.
PRKCQ Binding (association) of SNP associated with arthritis
1) Confidence 0.07 Published 2010 Journal Annals of the Rheumatic Diseases Section Body Doc Link PMC2935325 Disease Relevance 0.65 Pain Relevance 0.33

General Comments

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