INT329979

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Context Info
Confidence 0.31
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 3.51
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Fas) extracellular region (Fas) plasma membrane (Fas)
nucleus (Fas) cytoplasm (Fas)
Anatomy Link Frequency
Mouse 2
Fas (Mus musculus)
Pain Link Frequency Relevance Heat
Demyelination 2 75.60 Quite High
Inflammatory response 5 55.56 Quite High
Inflammation 19 50.00 Quite Low
Central nervous system 1 37.76 Quite Low
Spinal cord 81 12.72 Low Low
cytokine 15 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 105 99.08 Very High Very High Very High
Lymphatic System Cancer 95 98.40 Very High Very High Very High
Injury 33 97.44 Very High Very High Very High
Spinal Cord Injury 122 97.16 Very High Very High Very High
Death 15 84.56 Quite High
Thymoma 1 82.96 Quite High
Demyelinating Disease 2 75.60 Quite High
Wallerian Degeneration 1 62.84 Quite High
INFLAMMATION 25 55.20 Quite High
T-cell Lymphoma 11 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Mouse Fas-Fc- a competitive inhibitor of Fas-Fas-L interactions effectively inhibited apoptosis in the lymphomas studied confirming the involvement of the Fas-Fas-L pathway in apoptosis induced by bacterial Sags.
Negative_regulation (inhibitor) of Fas-Fc Binding (interactions) of in Mouse associated with lymphatic system cancer and apoptosis
1) Confidence 0.31 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3008744 Disease Relevance 1.13 Pain Relevance 0
Strategies to inhibit Fas–FasL interaction may be useful neuroprotective approaches for reducing apoptosis after SCI.
Negative_regulation (inhibit) of Fas Binding (interaction) of associated with spinal cord injury and apoptosis
2) Confidence 0.28 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2935363 Disease Relevance 2.38 Pain Relevance 0.10

General Comments

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