INT330041

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Context Info
Confidence 0.29
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.63
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Bax) endoplasmic reticulum (Bax) intracellular (Bax)
cytoplasm (Bax) cytosol (Bax) cell proliferation (Bax)
Bax (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Kinase C 42 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 102 100.00 Very High Very High Very High
Parkinson's Disease 4 97.32 Very High Very High Very High
Stress 36 91.72 High High
Necrosis 2 47.04 Quite Low
Death 22 31.28 Quite Low
Body Weight 56 5.00 Very Low Very Low Very Low
Hepatotoxicity 28 5.00 Very Low Very Low Very Low
Poisoning 18 5.00 Very Low Very Low Very Low
Toxicity 10 5.00 Very Low Very Low Very Low
Injury 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, taurine treatment inhibited As-induced up-regulation of Bad, Bax and down-regulation of Bcl-2, Bcl-xL.
Positive_regulation (induced) of Regulation (regulation) of Bax
1) Confidence 0.29 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2935368 Disease Relevance 0.71 Pain Relevance 0
We observed that NaAsO2 induced up-regulation of pro apoptotic (active non-phospho form of Bad, Bax) and down-regulation of anti apoptotic (active non-phospho form of Bcl-2, Bcl-xL) Bcl-2 family proteins both in vivo and in vitro (Fig. 5A, 5B, 5C, 5D).
Positive_regulation (induced) of Regulation (regulation) of Bax associated with apoptosis
2) Confidence 0.26 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2935368 Disease Relevance 0.92 Pain Relevance 0

General Comments

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