INT330051

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Context Info
Confidence 0.13
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.46
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Mapk8, Bcl2l11) mitochondrion (Mapk8, Bcl2l11) cytoplasm (Mapk8, Bcl2l11)
signal transduction (Mapk8) nucleus (Mapk8) kinase activity (Mapk8)
Mapk8 (Rattus norvegicus)
Bcl2l11 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Kinase C 21 91.04 High High
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 51 97.16 Very High Very High Very High
Death 11 97.00 Very High Very High Very High
Stress 18 53.68 Quite High
Poisoning 9 40.16 Quite Low
Body Weight 28 5.00 Very Low Very Low Very Low
Hepatotoxicity 14 5.00 Very Low Very Low Very Low
Toxicity 5 5.00 Very Low Very Low Very Low
Injury 5 5.00 Very Low Very Low Very Low
Parkinson's Disease 2 5.00 Very Low Very Low Very Low
Sprains And Strains 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These observations are in consistent with the data of other models where JNK-dependent Bim induction as well as phosphorylation with downstream activation of Bax-mediated apoptosis have been reported [39], [40].
JNK Positive_regulation (induction) of Bim associated with apoptosis
1) Confidence 0.13 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2935368 Disease Relevance 0.46 Pain Relevance 0.21

General Comments

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