INT3301

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Context Info
Confidence 0.55
First Reported 1978
Last Reported 2010
Negated 0
Speculated 1
Reported most in Abstract
Documents 26
Total Number 30
Disease Relevance 5.48
Pain Relevance 10.81

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transmembrane transport (Slc43a3)
Anatomy Link Frequency
reticular formation 1
neurons 1
brain structure 1
band 1
head 1
Slc43a3 (Mus musculus)
Pain Link Frequency Relevance Heat
isoflurane 38 100.00 Very High Very High Very High
opioid receptor 5 99.84 Very High Very High Very High
ketamine 13 99.76 Very High Very High Very High
Delta opioid receptors 5 99.76 Very High Very High Very High
halothane 9 99.68 Very High Very High Very High
tramadol 8 99.50 Very High Very High Very High
fluoxetine 12 99.40 Very High Very High Very High
bDMF 6 99.10 Very High Very High Very High
narcan 11 98.92 Very High Very High Very High
Morphine 20 98.86 Very High Very High Very High
Disease Link Frequency Relevance Heat
Shock 138 99.88 Very High Very High Very High
Anxiety Disorder 498 99.28 Very High Very High Very High
Dyspnea 1 99.28 Very High Very High Very High
Coma 2 97.04 Very High Very High Very High
Cognitive Disorder 28 96.88 Very High Very High Very High
Depression 13 94.76 High High
Sleep Disorders 20 94.56 High High
Injury 2 93.84 High High
Headache 1 90.88 High High
Decapitation 6 87.44 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This reduction suggests that EEG activation is less pronounced with this agent than with iopaminol.
Positive_regulation (activation) of EEG
1) Confidence 0.55 Published 1990 Journal J Neuroradiol Section Abstract Doc Link 2286841 Disease Relevance 0.24 Pain Relevance 0.13
We have previously shown that activation of mu 1-opioid receptors evoked EEG activation in the fetal lamb.
Positive_regulation (activation) of EEG associated with opioid receptor
2) Confidence 0.42 Published 1994 Journal Pharmacol. Biochem. Behav. Section Abstract Doc Link 7886089 Disease Relevance 0.09 Pain Relevance 0.54
Bolus injection and continuous infusion induced a significant increase of EEG discontinuity in preterm newborns affecting mean burst percentage and mean and maximum interburst duration.
Positive_regulation (increase) of EEG
3) Confidence 0.37 Published 2003 Journal Pediatrics Section Body Doc Link 12509564 Disease Relevance 0 Pain Relevance 0
This EEG activation was greatly attenuated at DPDPE doses greater than 154 nmol/h, resulting in a U-shaped dose-response curve.
Positive_regulation (activation) of EEG
4) Confidence 0.37 Published 1994 Journal Pharmacol. Biochem. Behav. Section Abstract Doc Link 7886089 Disease Relevance 0.07 Pain Relevance 0.63
These results indicate that the activation of delta-opioid receptors will evoke EEG activation in the fetal lamb.
Positive_regulation (activation) of EEG associated with delta opioid receptors
5) Confidence 0.37 Published 1994 Journal Pharmacol. Biochem. Behav. Section Abstract Doc Link 7886089 Disease Relevance 0.06 Pain Relevance 0.60
Tramadol may cause awareness and EEG activation during anaesthesia.
Positive_regulation (activation) of EEG associated with tramadol
6) Confidence 0.37 Published 1998 Journal Br J Anaesth Section Abstract Doc Link 10193286 Disease Relevance 0.34 Pain Relevance 0.81
The EEG activation was completely blocked by naloxone or naltrindole (delta antagonist), but not by naloxonazine (mu 1 antagonist).
Positive_regulation (activation) of EEG associated with antagonist and narcan
7) Confidence 0.37 Published 1994 Journal Pharmacol. Biochem. Behav. Section Abstract Doc Link 7886089 Disease Relevance 0.07 Pain Relevance 0.63
During hyperventilation induced by N2 inhalation a certain activation of the EEG was observed (spindles more pronounced, increased occurrence rate of discharges of the reticular activation system). 2.
Positive_regulation (activation) of EEG associated with dyspnea
8) Confidence 0.37 Published 1989 Journal Bratisl Lek Listy Section Abstract Doc Link 2720442 Disease Relevance 0.77 Pain Relevance 0.09
It is concluded that the report by Mikeska and Klemm of EEG activation in the decapitated head is correct, but that this phenomenon is also seen when the decapitated head is under deep anesthesia, and in normal brains under ether anesthesia or during REM sleep.
Positive_regulation (activation) of EEG in head associated with anesthesia
9) Confidence 0.37 Published 1992 Journal Neurotoxicol Teratol Section Abstract Doc Link 1522830 Disease Relevance 0.55 Pain Relevance 0.40
When infused ICV (4.6-154 nmol/h), DPDPE elicited dose-dependent activation of fetal EEG, with a reduction in power distribution in the delta (1-4 Hz) band, and an increase in the beta (15-32 Hz) band.
Positive_regulation (activation) of EEG in band
10) Confidence 0.37 Published 1994 Journal Pharmacol. Biochem. Behav. Section Abstract Doc Link 7886089 Disease Relevance 0.08 Pain Relevance 0.63
On the other hand, when the EEG was activated by discontinuation of propofol, the corresponding alpha-peaks disappeared.
Positive_regulation (activated) of EEG
11) Confidence 0.20 Published 2007 Journal Acta Anaesthesiol Scand Section Body Doc Link 17378787 Disease Relevance 0 Pain Relevance 0
This study was designed to examine the effect of ketamine on the spindle oscillations to understand the simultaneous sedative effect and EEG activation that occurs with ketamine, by comparing the EEG in emergence.
Positive_regulation (activation) of EEG associated with ketamine
12) Confidence 0.20 Published 2007 Journal Acta Anaesthesiol Scand Section Abstract Doc Link 17378787 Disease Relevance 0 Pain Relevance 0.26
During the transition from waking to sleep, they stopped firing before the onset of EEG synchronization, the first sign of EEG sleep, while, during the transition from sleep to waking, they discharged not before, but after, onset of EEG activation, the first sign of EEG waking (Figure 4).
Positive_regulation (activation) of EEG
13) Confidence 0.17 Published 2010 Journal Frontiers in Behavioral Neuroscience Section Body Doc Link PMC2972729 Disease Relevance 0 Pain Relevance 0.07
At the transition from SWS to W, they discharged after the onset of EEG activation, the first EEG sign of W.
Positive_regulation (activation) of EEG
14) Confidence 0.17 Published 2010 Journal Frontiers in Behavioral Neuroscience Section Abstract Doc Link PMC2972729 Disease Relevance 0.13 Pain Relevance 0.12
The interval between the first unit discharge and the onset of EEG activation in these W-specific neurons decreased in the order NE–LC?
Positive_regulation (activation) of EEG in neurons associated with locus ceruleus
15) Confidence 0.17 Published 2010 Journal Frontiers in Behavioral Neuroscience Section Body Doc Link PMC2972729 Disease Relevance 0.05 Pain Relevance 0.24
At the transition from SWS to W, they discharged after the onset of EEG activation, the first EEG sign of W.
Positive_regulation (activation) of EEG
16) Confidence 0.12 Published 2010 Journal Frontiers in Behavioral Neuroscience Section Abstract Doc Link PMC2972729 Disease Relevance 0.13 Pain Relevance 0.12
Patients with baseline delta EEG power less than 80% of total power showed increases in delta EEG and decreases in median frequency with isoflurane and desflurane.
Positive_regulation (increases) of EEG associated with isoflurane
17) Confidence 0.09 Published 1995 Journal Anesth. Analg. Section Abstract Doc Link 7574015 Disease Relevance 0 Pain Relevance 0.43
The EEG was recorded from frontal leads and processed variables were analyzed as a function of increasing isoflurane and desflurane concentration with age and baseline delta EEG power (0.5-3.75 Hz) as independent variables.
Spec (analyzed) Positive_regulation (increasing) of EEG associated with isoflurane
18) Confidence 0.09 Published 1995 Journal Anesth. Analg. Section Abstract Doc Link 7574015 Disease Relevance 0 Pain Relevance 0.25
We hypothesized that isoflurane, more than halothane, would depress EEG activation elicited by electrical microstimulation of the reticular formation.
Positive_regulation (activation) of EEG in reticular formation associated with halothane and isoflurane
19) Confidence 0.09 Published 2006 Journal Anesth. Analg. Section Abstract Doc Link 16717314 Disease Relevance 0.19 Pain Relevance 0.64
This result demonstrates that genetic enhancement of learning and memory (Figure 3A) also potentiates EEG activity during subsequent sleep in CaMKIV over-expressed mice, linking genetics, sleep and memory through the CaMKIV protein.
Positive_regulation (potentiates) of EEG
20) Confidence 0.07 Published 2010 Journal Mol Brain Section Body Doc Link PMC2888801 Disease Relevance 0.29 Pain Relevance 0

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