INT330101

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Context Info
Confidence 0.16
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.43
Pain Relevance 0.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Map3k11, Rac1) cell proliferation (Map3k11, Rac1) intracellular (Rac1)
enzyme binding (Rac1) GTPase activity (Rac1) cell death (Map3k11)
Map3k11 (Rattus norvegicus)
Rac1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ischemia 172 99.90 Very High Very High Very High
Hippocampus 34 24.04 Low Low
cerebral cortex 4 13.80 Low Low
anesthesia 8 5.00 Very Low Very Low Very Low
Pyramidal cell 6 5.00 Very Low Very Low Very Low
isoflurane 6 5.00 Very Low Very Low Very Low
Intracerebroventricular 4 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv General 4 Under Development 110 99.90 Very High Very High Very High
Cognitive Disorder 24 91.00 High High
Stress 52 90.72 High High
Cv Unclassified Under Development 60 89.36 High High
Apoptosis 12 79.76 Quite High
Death 38 77.84 Quite High
Reperfusion Injury 12 62.32 Quite High
Stroke 16 28.48 Quite Low
Targeted Disruption 4 18.04 Low Low
Injury 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For instance, previous work by our group has shown that Rac1 GTPase also has an important role in activation of the proapoptotic JNK signaling pathway following cerebral ischemia, as Rac1 binds to a scaffold complex of POSH and MLK3 and facilitates activation of JNK [7], [32].
MLK3 Binding (complex) of Rac1 associated with cv general 4 under development and ischemia
1) Confidence 0.16 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2935374 Disease Relevance 1.21 Pain Relevance 0.31
For instance, previous work by our group has shown that Rac1 GTPase also has an important role in activation of the proapoptotic JNK signaling pathway following cerebral ischemia, as Rac1 binds to a scaffold complex of POSH and MLK3 and facilitates activation of JNK [7], [32].
MLK3 Binding (binds) of Rac1 associated with cv general 4 under development and ischemia
2) Confidence 0.16 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2935374 Disease Relevance 1.21 Pain Relevance 0.31

General Comments

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