INT330333

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Context Info
Confidence 0.17
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.57
Pain Relevance 0.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Lap2 (Mus musculus)
Pain Link Frequency Relevance Heat
neurotrophin 3 5 99.92 Very High Very High Very High
diabetic neuropathy 4 97.24 Very High Very High Very High
Pain 16 91.04 High High
Nerve growth factor 10 87.96 High High
Lasting pain 4 83.04 Quite High
Neurotransmitter 3 33.84 Quite Low
Inflammation 12 31.76 Quite Low
bDMF 1 31.60 Quite Low
opioid receptor 1 17.60 Low Low
Spinal cord 4 9.60 Low Low
Disease Link Frequency Relevance Heat
Cold Sores 367 98.96 Very High Very High Very High
Diabetic Neuropathy 4 97.24 Very High Very High Very High
Diabetes Mellitus 10 92.56 High High
Overactive Bladder 1 92.08 High High
Pain 20 91.68 High High
Neuropathic Pain 7 72.00 Quite High
INFLAMMATION 15 31.76 Quite Low
Nociception 2 11.92 Low Low
Cancer 202 5.00 Very Low Very Low Very Low
Infection 67 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In a further study aimed to determine whether an HSV latency promoter can prolong expression of neurotrophin 3 (NT-3), it has been shown that the continuous production of NT-3 by Lap2-driven long-term expression of the transgene from an HSV vector protects against progression of diabetic neuropathy in mice [31].


Gene_expression (expression) of Lap2 associated with cold sores, neurotrophin 3 and diabetic neuropathy
1) Confidence 0.17 Published 2010 Journal The Open Virology Journal Section Body Doc Link PMC2936037 Disease Relevance 1.57 Pain Relevance 0.69

General Comments

This test has worked.

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