INT330380

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Context Info
Confidence 0.17
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.78
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CD40) extracellular region (CD40) plasma membrane (CD40)
enzyme binding (CD40) protein complex assembly (CD40) signal transducer activity (CD40)
Anatomy Link Frequency
monocyte 2
CD40 (Homo sapiens)
IFNA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 42 81.76 Quite High
agonist 1 69.60 Quite High
central nervous system 21 52.16 Quite High
imagery 27 5.00 Very Low Very Low Very Low
Pain 16 5.00 Very Low Very Low Very Low
inflammatory 12 5.00 Very Low Very Low Very Low
positron emission tomography 12 5.00 Very Low Very Low Very Low
nerve growth factor 10 5.00 Very Low Very Low Very Low
Peripheral nervous system 8 5.00 Very Low Very Low Very Low
Multiple sclerosis 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Viral Meningitis 4 85.84 High High
Cold Sores 367 85.24 High High
Meningitis 1 70.08 Quite High
Infection 67 59.12 Quite High
Virus Diseases 2 52.72 Quite High
Death 6 47.04 Quite Low
Apoptosis 30 45.32 Quite Low
Cancer 202 5.00 Very Low Very Low Very Low
Disease 34 5.00 Very Low Very Low Very Low
Pain 20 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Recently, it has been shown that the complex of the four glycoproteins gB, gD, gH and gL, which are essential for viral attachment/entry (Fig. 3), expressed on the surface of Cos7 cells mediates monocyte-derived DC recognition via a nucleic acid-independent and TLR-independent pathway, leading to the up-regulation of CD40, CD83, CD86 and HLA-DR and to the production of IFN-?
CD40 Regulation (regulation) of Gene_expression (production) of IFN in monocyte
1) Confidence 0.17 Published 2010 Journal The Open Virology Journal Section Body Doc Link PMC2936037 Disease Relevance 0.78 Pain Relevance 0.10

General Comments

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