INT330430

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.47
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeletal protein binding (ALDOA) cytosol (ALDOA) small molecule metabolic process (ALDOA)
lyase activity (ALDOA) extracellular region (ALDOA) biosynthetic process (Pcyt2)
ALDOA (Homo sapiens)
Pcyt2 (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 11 96.76 Very High Very High Very High
Potency 1 78.72 Quite High
Angina 5 58.84 Quite High
alcohol 9 20.32 Low Low
agonist 2 5.00 Very Low Very Low Very Low
Dopamine 2 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
noradrenaline 1 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
gABA 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 3 92.00 High High
Increased Venous Pressure Under Development 3 86.92 High High
Targeted Disruption 10 61.20 Quite High
Cardiovascular Disease 7 60.12 Quite High
Cv General 3 Under Development 5 58.84 Quite High
Myocardial Infarction 11 37.76 Quite Low
Toxicity 9 18.32 Low Low
Cv Unclassified Under Development 15 9.36 Low Low
Stress 23 5.44 Low Low
Heart Disease 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Since Alda-1 activates both the dehydrogenase activity and esterase activity of ALDH2,9,68 Beretta et al. evaluated the effect of Alda-1 on bioactivation of nitroglyercin.69 Surprisingly, Alda-1 failed to increase GTN denitration and bioactivation in these assays using either the ALDH2 wild-type and ALDH2*2 recombinant enzyme in vitro.
Alda-1 Positive_regulation (activates) of et
1) Confidence 0.01 Published 2010 Journal Cardiovascular Research Section Body Doc Link PMC2936126 Disease Relevance 0.47 Pain Relevance 0.17

General Comments

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