INT330442

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Context Info
Confidence 0.37
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.69
Pain Relevance 1.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Trpv1) transport (Trpv1) plasma membrane (Trpv1)
transmembrane transport (Trpv1) lipid metabolic process (Trpv1)
Anatomy Link Frequency
neurons 2
Trpv1 (Mus musculus)
Pain Link Frequency Relevance Heat
dorsal root ganglion 22 100.00 Very High Very High Very High
Cancer pain 1 99.86 Very High Very High Very High
Hyperalgesia 3 98.94 Very High Very High Very High
Dorsal horn 16 95.72 Very High Very High Very High
Spinal cord 27 95.60 Very High Very High Very High
Thermal hyperalgesia 4 91.24 High High
allodynia 3 90.24 High High
Sciatic nerve 2 82.28 Quite High
Eae 3 81.44 Quite High
Neuropathic pain 2 80.08 Quite High
Disease Link Frequency Relevance Heat
Ganglion Cysts 22 100.00 Very High Very High Very High
Cancer Pain 1 99.86 Very High Very High Very High
Targeted Disruption 2 99.60 Very High Very High Very High
Hyperalgesia 7 98.94 Very High Very High Very High
Neuropathic Pain 8 90.24 High High
Injury 2 81.44 Quite High
Syndrome 1 69.24 Quite High
Cancer 6 51.28 Quite High
Necrosis 3 50.00 Quite Low
Pain 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A role for TNFR2 receptors in heat hyperalgesia has been implicated in a model of cancer pain where TRPV1 protein up-regulation in DRG neurons is attenuated in TNFR2 knock-out mice [4].
Negative_regulation (attenuated) of Regulation (regulation) of TRPV1 protein in neurons associated with targeted disruption, dorsal root ganglion, hyperalgesia and cancer pain
1) Confidence 0.37 Published 2010 Journal J Neuroinflammation Section Body Doc Link PMC2936303 Disease Relevance 1.69 Pain Relevance 1.38

General Comments

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