INT330457

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Context Info
Confidence 0.08
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.70
Pain Relevance 0.97

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
brain 1
NSC 1
parenchyma 1
RT1-CE1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Nerve growth factor 174 99.38 Very High Very High Very High
ischemia 21 93.48 High High
Inflammation 9 76.16 Quite High
Central nervous system 24 73.28 Quite High
Inflammatory response 3 36.80 Quite Low
Hippocampus 9 5.00 Very Low Very Low Very Low
palliative 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 12 97.16 Very High Very High Very High
Brain Hemorrhage 12 93.48 High High
Stress 9 89.12 High High
INFLAMMATION 12 76.16 Quite High
Stroke 27 53.96 Quite High
Death 6 39.04 Quite Low
Apoptosis 3 38.60 Quite Low
Cv Unclassified Under Development 9 5.00 Very Low Very Low Very Low
Neurological Disease 6 5.00 Very Low Very Low Very Low
Infarction 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our results show an up-regulation of class I MHC in the ischemic rats with NGF and NSC administration.
Regulation (regulation) of class I MHC in NSC associated with nerve growth factor
1) Confidence 0.08 Published 2010 Journal J Transl Med Section Abstract Doc Link PMC2936305 Disease Relevance 0.15 Pain Relevance 0.37
The up-regulation of the class I MHC correlated well with the symptomatic relief in ischemic rats given the NSC transplant and the upsurge of NGF in vivo, suggesting an immuno-modulation of the class I MHC by NSC-derived neurotrophins in the micro-environment of the lesioned brain parenchyma.
Regulation (modulation) of class I MHC in parenchyma associated with nerve growth factor
2) Confidence 0.08 Published 2010 Journal J Transl Med Section Body Doc Link PMC2936305 Disease Relevance 0.30 Pain Relevance 0.33
The up-regulation of the class I MHC correlated well with the symptomatic relief in ischemic rats given the NSC transplant and the upsurge of NGF in vivo, suggesting an immuno-modulation of the class I MHC by NSC-derived neurotrophins in the micro-environment of the lesioned brain parenchyma.
Regulation (regulation) of class I MHC in brain associated with nerve growth factor
3) Confidence 0.07 Published 2010 Journal J Transl Med Section Body Doc Link PMC2936305 Disease Relevance 0.25 Pain Relevance 0.27

General Comments

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