INT330519

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Context Info
Confidence 0.08
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.99
Pain Relevance 0.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (DICER1) extracellular region (CD8A) intracellular (DICER1)
helicase activity (DICER1) plasma membrane (CD8A) cytoplasm (DICER1)
Anatomy Link Frequency
T cell 1
CD8A (Homo sapiens)
DICER1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Arthritis 55 98.00 Very High Very High Very High
Multiple sclerosis 1 56.48 Quite High
Inflammation 5 5.00 Very Low Very Low Very Low
rheumatoid arthritis 4 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
Rheumatism 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 57 98.00 Very High Very High Very High
Disease 11 91.80 High High
Apoptosis 10 60.32 Quite High
Demyelinating Disease 1 56.48 Quite High
Death 11 50.00 Quite Low
Benign Prostatic Hypertrophy 1 33.88 Quite Low
Reprotox - General 1 4 30.96 Quite Low
Autoimmune Disease 8 5.00 Very Low Very Low Very Low
INFLAMMATION 6 5.00 Very Low Very Low Very Low
Systemic Lupus Erythematosus 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Intriguingly, only the CD8+ T cell associated DR4, DcR1 and DcR2 expression levels correlated with DAS28 scores in patients with RA, implying that altered TRAIL receptor profiles on CD8+ T cell subsets rather than on CD4+ T cells is more important in terms of disease severity.


CD8 Binding (associated) of DcR1 in T cell associated with disease and arthritis
1) Confidence 0.08 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2936350 Disease Relevance 0.99 Pain Relevance 0.38

General Comments

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