INT330620

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Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.92
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (S100a8, TNF) extracellular region (S100a8, TNF) plasma membrane (S100a8, TNF)
signal transduction (TNF) intracellular (TNF) cytoskeleton (S100a8)
Anatomy Link Frequency
macrophages 2
S100a8 (Mus musculus)
TNF (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 39 100.00 Very High Very High Very High
cytokine 20 100.00 Very High Very High Very High
chemokine 2 97.20 Very High Very High Very High
tolerance 5 5.00 Very Low Very Low Very Low
withdrawal 3 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 41 100.00 Very High Very High Very High
Necrosis 1 100.00 Very High Very High Very High
Cancer 1 100.00 Very High Very High Very High
Obesity 33 97.90 Very High Very High Very High
Insulin Resistance 8 69.04 Quite High
Cardiovascular Disease 1 68.76 Quite High
Diabetes Mellitus 29 67.64 Quite High
Dyslipidemia /

Combined Dyslipidemia

1 66.96 Quite High
Fatty Liver 1 66.40 Quite High
Metabolic Disorder 6 64.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Enlarged adipocytes, together with the infiltrated macrophages, act in a synergistic manner to cause aberrant production of pro-inflammatory molecules including inducible nitric oxide, cytokines such as tumor necrosis factor-alpha (TNF-?)
pro-inflammatory Positive_regulation (molecules) of Positive_regulation (inducible) of TNF in macrophages associated with necrosis, inflammation, cancer, obesity and cytokine
1) Confidence 0.03 Published 2010 Journal Nutr Metab (Lond) Section Body Doc Link PMC2936435 Disease Relevance 1.86 Pain Relevance 0.32

General Comments

This test has worked.

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