INT330629

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Context Info
Confidence 0.30
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.76
Pain Relevance 0.94

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

DNA binding (TP53, Fos) nucleus (TP53, Fos) nucleolus (TP53, Fos)
transcription factor binding (TP53, Fos) cell differentiation (TP53) nucleoplasm (TP53)
TP53 (Homo sapiens)
Fos (Rattus norvegicus)
Pain Link Frequency Relevance Heat
depression 21 99.48 Very High Very High Very High
Hippocampus 28 99.16 Very High Very High Very High
Pyramidal cell 10 98.88 Very High Very High Very High
Pain 19 92.24 High High
long-term potentiation 14 78.88 Quite High
phantom pain 1 72.56 Quite High
Glutamate receptor 2 64.56 Quite High
Dopamine 2 51.96 Quite High
nMDA receptor 5 48.60 Quite Low
dopamine receptor 1 43.08 Quite Low
Disease Link Frequency Relevance Heat
Li-fraumeni Syndrome 21 100.00 Very High Very High Very High
Depression 21 99.48 Very High Very High Very High
Nociception 33 99.20 Very High Very High Very High
Pain 20 92.24 High High
Anxiety Disorder 6 89.84 High High
Amputation 1 80.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, LFS decreased Fos expression and induced LTD of nociceptive responses.
LFS Negative_regulation (decreased) of Gene_expression (expression) of Fos associated with nociception, li-fraumeni syndrome and depression
1) Confidence 0.30 Published 2010 Journal BMC Neurosci Section Body Doc Link PMC2936438 Disease Relevance 1.76 Pain Relevance 0.94

General Comments

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