INT330697

Context Info Confidence 0.00 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.30 Pain Relevance 0

cytoplasm (PCNA, INCENP) nucleus (PCNA, INCENP) nucleoplasm (PCNA) chromosome segregation (INCENP) DNA binding (PCNA) protein complex (INCENP)

PCNA (Homo sapiens) INCENP (Homo sapiens)

Pain Link Frequency Relevance Heat Pain 1 5.00

Disease Link Frequency Relevance Heat Cancer 6 99.50 Retinoblastoma 51 99.36 Apoptosis 2 30.24 Infection 11 5.00 Viral Infection 10 5.00 Epstein-barr Virus 4 5.00 Stress 2 5.00 Herpes Zoster 2 5.00 Leukemia 2 5.00 Osteogenic Sarcomas 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Recently, the CHPK encoded by the UL97 gene of HHV-5 (HCMV) was shown to directly phosphorylate the cellular retinoblastoma (Rb) tumor suppressor protein both in vivo and in vitro, on residues that are normally targeted by the cellular cyclin-dependent kinase (Cdk) proteins that control cell cycle progression [46], [47].

cyclin Regulation (targeted) of in vivo associated with cancer and retinoblastoma

1) Confidence 0.00 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2936540 Disease Relevance 0.30 Pain Relevance 0

General Comments

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