INT331103

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Context Info
Confidence 0.61
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.10
Pain Relevance 1.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (Mc1r) signal transduction (Mc1r) plasma membrane (Mc1r)
signal transducer activity (Mc1r)
Anatomy Link Frequency
nerve 2
Mc1r (Mus musculus)
Pain Link Frequency Relevance Heat
melanocortin 1 receptor 70 100.00 Very High Very High Very High
Spinal cord 4 97.64 Very High Very High Very High
antagonist 5 77.16 Quite High
Neuropathic pain 7 76.08 Quite High
agonist 9 70.96 Quite High
Lasting pain 1 67.96 Quite High
Inflammation 19 64.32 Quite High
Inflammatory response 1 62.96 Quite High
nociceptor 3 57.12 Quite High
TRP channel 4 50.80 Quite High
Disease Link Frequency Relevance Heat
Injury 18 98.84 Very High Very High Very High
Sprains And Strains 10 94.16 High High
Nervous System Injury 2 93.08 High High
Neuropathic Pain 22 76.08 Quite High
Pain 24 67.96 Quite High
INFLAMMATION 20 64.32 Quite High
Nociception 13 47.68 Quite Low
Obesity 4 19.36 Low Low
Hyperalgesia 13 5.00 Very Low Very Low Very Low
Inflammatory Pain 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Following axotomy, no alteration in MC1R mRNA expression is seen in dorsal root ganglia and decreases in both MC2R and MC3R, but MC4R mRNA increases following axotomy [48], perhaps suggesting a greater role for MC4R than MC1R in nerve injury.
Neg (no) Regulation (alteration) of Transcription (expression) of MC1R in nerve associated with nervous system injury and melanocortin 1 receptor
1) Confidence 0.61 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2938350 Disease Relevance 1.10 Pain Relevance 1.09

General Comments

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