INT331107

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Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.50
Pain Relevance 1.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (Mc1r) signal transduction (Mc1r) plasma membrane (Mc1r)
molecular_function (Vmn1r71) cellular_component (Vmn1r71) signal transducer activity (Mc1r)
Vmn1r71 (Mus musculus)
Mc1r (Mus musculus)
Pain Link Frequency Relevance Heat
melanocortin 1 receptor 70 90.68 High High
qutenza 24 81.28 Quite High
Inflammation 19 61.28 Quite High
Pain 21 60.12 Quite High
agonist 9 38.24 Quite Low
Eae 16 5.00 Very Low Very Low Very Low
tolerance 14 5.00 Very Low Very Low Very Low
withdrawal 13 5.00 Very Low Very Low Very Low
allodynia 12 5.00 Very Low Very Low Very Low
analgesia 9 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nociception 13 94.16 High High
Targeted Disruption 6 91.96 High High
Neuropathic Pain 22 61.92 Quite High
INFLAMMATION 20 61.28 Quite High
Pain 24 60.12 Quite High
Obesity 4 33.60 Quite Low
Injury 18 5.00 Very Low Very Low Very Low
Hyperalgesia 13 5.00 Very Low Very Low Very Low
Sprains And Strains 10 5.00 Very Low Very Low Very Low
Inflammatory Pain 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Recessive yellow mice, Mc1re, are homozygous for the Mc1re allele and lack functional Mc1r by virtue of a single base deletion in the Mc1r gene which produces a frameshift at amino acid 183 and truncation of the receptor in the second extracellular loop between transmembrane domains 4 and 5.
Mc1re Positive_regulation (lack) of Mc1r
1) Confidence 0.05 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2938350 Disease Relevance 0.50 Pain Relevance 1.05

General Comments

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