INT331146

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Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.39
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

kinase activity (Ttbk2) cellular_component (Ttbk2)
Anatomy Link Frequency
covering 1
Ttbk2 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 4 50.00 Quite Low
Pyramidal cell 12 5.00 Very Low Very Low Very Low
Hippocampus 3 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 15 89.76 High High
Parkinson's Disease 1 83.68 Quite High
Tauopathy 26 75.16 Quite High
Neurodegenerative Disease 2 74.68 Quite High
Death 12 64.16 Quite High
INFLAMMATION 5 50.00 Quite Low
Disease 29 45.44 Quite Low
Frailty 1 35.92 Quite Low
Dementia 4 34.40 Quite Low
Retinoblastoma 1 11.96 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The data explain how excess Tau in first instance blocks transport by covering microtubuli, while GSK3 acting as major Tau-kinase I phosphorylates Tau to detach it from the microtubules and relieves the transport blockade [37].
Phosphorylation (phosphorylates) of Tau-kinase in covering
1) Confidence 0.03 Published 2010 Journal International Journal of Alzheimer's Disease Section Body Doc Link PMC2938448 Disease Relevance 0.39 Pain Relevance 0

General Comments

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