INT331147

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Context Info
Confidence 0.45
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.60
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein targeting (YWHAQ) nucleolus (YWHAQ) nucleus (YWHAQ)
protein complex (YWHAQ) cytoplasm (YWHAQ)
YWHAQ (Homo sapiens)
Pain Link Frequency Relevance Heat
Hippocampus 3 97.36 Very High Very High Very High
Pyramidal cell 12 92.72 High High
Inflammation 4 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Amyloid Plaque 8 94.12 High High
Alzheimer's Dementia 32 88.80 High High
Disease 29 69.72 Quite High
Targeted Disruption 15 24.60 Low Low
Tauopathy 26 15.84 Low Low
Death 12 5.00 Very Low Very Low Very Low
Cognitive Disorder 8 5.00 Very Low Very Low Very Low
INFLAMMATION 5 5.00 Very Low Very Low Very Low
Dementia 4 5.00 Very Low Very Low Very Low
Frontotemporal Dementia 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
At this late time-point, we also observed increased phosphorylation of endogenous mouse protein Tau, particularly at residues T181 and T231, both known to be substrate for GSK3.
Positive_regulation (increased) of Phosphorylation (phosphorylation) of protein Tau
1) Confidence 0.45 Published 2010 Journal International Journal of Alzheimer's Disease Section Body Doc Link PMC2938448 Disease Relevance 0.60 Pain Relevance 0.18

General Comments

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