INT331204

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Context Info
Confidence 0.04
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.64
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (Htt) endoplasmic reticulum (Htt) mitochondrion organization (Htt)
embryo development (Htt) protein complex (Htt) cytoplasm (Htt)
Htt (Mus musculus)
Pain Link Frequency Relevance Heat
carbamazepine 1 81.52 Quite High
Clonidine 1 5.00 Very Low Very Low Very Low
Substantia nigra 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Toxicity 9 99.48 Very High Very High Very High
Disease 15 98.12 Very High Very High Very High
Neurodegenerative Disease 16 97.76 Very High Very High Very High
Stress 4 82.48 Quite High
Apoptosis 5 58.52 Quite High
Death 4 53.68 Quite High
Alzheimer's Dementia 18 28.08 Quite Low
Parkinson's Disease 9 5.00 Very Low Very Low Very Low
Starvation 6 5.00 Very Low Very Low Very Low
Multiple Sulfatase Deficiency Disease 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Another compound, trehalose, inhibits aggregation of mutant huntingtin and reduces toxicity in cells, and alleviates disease pathology in an HD mouse model [75].
Negative_regulation (inhibits) of huntingtin Binding (aggregation) of associated with toxicity and disease
1) Confidence 0.04 Published 2010 Journal Seminars in Cell & Developmental Biology Section Body Doc Link PMC2938570 Disease Relevance 0.64 Pain Relevance 0.04

General Comments

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