INT331227

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Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.13
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Becn1, Pink1) mitochondrion (Pink1) Golgi apparatus (Becn1)
protein complex (Becn1) response to stress (Pink1) cytosol (Pink1)
Becn1 (Mus musculus)
Pink1 (Mus musculus)
Pain Link Frequency Relevance Heat
Substantia nigra 1 90.72 High High
carbamazepine 1 5.00 Very Low Very Low Very Low
Clonidine 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Parkinson's Disease 9 99.24 Very High Very High Very High
Death 4 88.80 High High
Alzheimer's Dementia 18 86.04 High High
Disease 15 67.36 Quite High
Targeted Disruption 4 42.28 Quite Low
Amyloid Plaque 1 9.16 Low Low
Frailty 1 8.52 Low Low
Dementia 1 6.60 Low Low
Neurodegenerative Disease 16 5.08 Very Low Very Low Very Low
Toxicity 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Full-length PINK1 interacts with Beclin 1 and this appears to act as a positive mediator of autophagy.
Beclin 1 Binding (interacts) of PINK1
1) Confidence 0.03 Published 2010 Journal Seminars in Cell & Developmental Biology Section Body Doc Link PMC2938570 Disease Relevance 1.13 Pain Relevance 0.05

General Comments

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