INT331230

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.77
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Mapk8, Becn1) mitochondrion (Mapk8) Golgi apparatus (Becn1)
protein complex (Becn1) cytosol (Mapk8) signal transduction (Mapk8)
Mapk8 (Mus musculus)
Becn1 (Mus musculus)
Pain Link Frequency Relevance Heat
carbamazepine 1 5.00 Very Low Very Low Very Low
Clonidine 1 5.00 Very Low Very Low Very Low
Substantia nigra 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Starvation 6 99.32 Very High Very High Very High
Apoptosis 5 96.36 Very High Very High Very High
Stress 4 88.88 High High
Dna Damage 1 79.92 Quite High
Cancer 4 75.48 Quite High
Tuberous Sclerosis 1 38.80 Quite Low
Alzheimer's Dementia 18 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 16 5.00 Very Low Very Low Very Low
Disease 15 5.00 Very Low Very Low Very Low
Parkinson's Disease 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Starvation induces Jun N-terminal kinase 1 (Jnk1) activity, which phosphorylates Bcl-2, thereby disrupting the interaction between Beclin 1 and Bcl-2 to induce autophagy [21].
Jnk1 Binding (interaction) of Beclin 1 associated with starvation
1) Confidence 0.02 Published 2010 Journal Seminars in Cell & Developmental Biology Section Body Doc Link PMC2938570 Disease Relevance 0.77 Pain Relevance 0

General Comments

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