INT331291

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Context Info
Confidence 0.35
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.99
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

structural molecule activity (KRT39)
KRT39 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Visceral Leishmaniasis 282 97.88 Very High Very High Very High
Disease 54 70.68 Quite High
Infection 21 68.08 Quite High
Bites And Stings 9 5.00 Very Low Very Low Very Low
Malaria 9 5.00 Very Low Very Low Very Low
Mycobacterial Infection 9 5.00 Very Low Very Low Very Low
Splenomegaly 6 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Anaemia 3 5.00 Very Low Very Low Very Low
Communicable Diseases 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The benefit of using rK28 for VL diagnosis arises from its ability to capture circulating antibodies to 3 Leishmania antigens compared to rK39, which binds antibodies specific to a single antigen.
rK39 Binding (binds) of associated with visceral leishmaniasis
1) Confidence 0.35 Published 2010 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2939046 Disease Relevance 0.38 Pain Relevance 0
ELISA test results with Sudanese sera on rK28, rK39, rK26, and rK9
rK39 Binding (results) of
2) Confidence 0.27 Published 2010 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2939046 Disease Relevance 0.19 Pain Relevance 0
The cumulative antibody binding observed with rK28 raises the intensity of the signal and makes the border-line positive low rK39 sera distinctly positive.
rK39 Binding (binding) of
3) Confidence 0.26 Published 2010 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2939046 Disease Relevance 0.42 Pain Relevance 0

General Comments

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