INT331293

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Context Info
Confidence 0.49
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 5
Disease Relevance 1.39
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

structural molecule activity (KRT39)
KRT39 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 10 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 35 99.26 Very High Very High Very High
Visceral Leishmaniasis 470 98.98 Very High Very High Very High
Communicable Diseases 5 85.92 High High
Disease 90 83.28 Quite High
Bites And Stings 15 5.00 Very Low Very Low Very Low
Malaria 15 5.00 Very Low Very Low Very Low
Mycobacterial Infection 15 5.00 Very Low Very Low Very Low
Splenomegaly 10 5.00 Very Low Very Low Very Low
Pain 5 5.00 Very Low Very Low Very Low
Anaemia 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Sudanese parasitology confirmed VL-positive and -negative sera (NHS, EC, NEC and other infection sera) were tested by ELISA on rK28, rK39, rK26, and rK9 to evaluate immunoreactivities (expressed as A450nm in Fig. 2) against individual proteins.
Gene_expression (expressed) of rK39 associated with visceral leishmaniasis and infection
1) Confidence 0.49 Published 2010 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2939046 Disease Relevance 0.29 Pain Relevance 0
For many of the Sudanese VL sera tested, the relative absorbance observed were higher on the rK28 ELISA compared to rK39, rK26 or rK9.
Gene_expression (higher) of rK39 associated with visceral leishmaniasis
2) Confidence 0.49 Published 2010 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2939046 Disease Relevance 0.19 Pain Relevance 0
ELISA test results with Sudanese sera on rK28, rK39, rK26, and rK9
Gene_expression (rK9) of rK39
3) Confidence 0.49 Published 2010 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2939046 Disease Relevance 0.20 Pain Relevance 0
All healthy U.S donors (30 samples) were test-negative on rK39, rK28 and rK26 ELISA. rK9 was least specific, as 4/30 U.S donors reacted non-specifically on the ELISA (data not shown).
Neg (negative) Gene_expression (negative) of rK39
4) Confidence 0.49 Published 2010 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2939046 Disease Relevance 0.24 Pain Relevance 0
We next sought to determine whether VL sera with low/borderline ELISA reactivity against rK39 could be detected with greater accuracy using rK28.
Gene_expression (detected) of rK39 associated with visceral leishmaniasis
5) Confidence 0.44 Published 2010 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2939046 Disease Relevance 0.48 Pain Relevance 0

General Comments

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