INT331330

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Context Info
Confidence 0.57
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.20
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.


Pain Term Frequency Confidence Heat
Potency 5 98.62 Very High Very High Very High
Inflammation 2 73.72 Quite High
addiction 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Glutamate 5 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Bioavailability 2 5.00 Very Low Very Low Very Low
Disease Term Frequency Confidence Heat
INFLAMMATION 2 73.72 Quite High
Infection 18 55.60 Quite High
Disease 16 46.36 Quite Low
Heart Disease 1 5.00 Very Low Very Low Very Low
Bites And Stings 1 5.00 Very Low Very Low Very Low
Parasitemia 1 5.00 Very Low Very Low Very Low
Body Weight 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
American Trypanosomiasis 5 5.00 Very Low Very Low Very Low
Parasitic Infection 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, potency of WRR-483 against papain, cathepsins L and V were moderate, and no inhibition of other cysteine proteases, including calpain-1, cathepsins H and K, was observed.
Negative_regulation (inhibition) of cathepsins H associated with potency
1) Confidence 0.57 Published 2010 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2939063 Disease Relevance 0.20 Pain Relevance 0.12

General Comments

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