INT331339

Context Info Confidence 0.02 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.61 Pain Relevance 0.05

Mir483 (Mus musculus)

Pain Link Frequency Relevance Heat Potency 5 92.32 Glutamate 5 5.00 Inflammation 2 5.00 alcohol 2 5.00 Bioavailability 2 5.00 addiction 1 5.00 anesthesia 1 5.00

Disease Link Frequency Relevance Heat Disease 16 98.64 Infection 18 95.80 American Trypanosomiasis 5 86.36 INFLAMMATION 2 5.00 Parasitic Infection 2 5.00 Heart Disease 1 5.00 Bites And Stings 1 5.00 Parasitemia 1 5.00 Body Weight 1 5.00 Death 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

WRR-483, an analog of K11777, was synthesized and evaluated as an inhibitor of cruzain and against T. cruzi proliferation in cell culture.

Negative_regulation (inhibitor) of Gene_expression (synthesized) of WRR-483

1) Confidence 0.02 Published 2010 Journal PLoS Neglected Tropical Diseases Section Abstract Doc Link PMC2939063 Disease Relevance 0.61 Pain Relevance 0.05

General Comments

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