INT331348

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (BC051665) molecular_function (BC051665) cellular_component (BC051665)
biological_process (BC051665)
Mir483 (Mus musculus)
BC051665 (Mus musculus)
Pain Link Frequency Relevance Heat
Glutamate 5 63.00 Quite High
Potency 5 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Bioavailability 2 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 16 13.76 Low Low
Infection 18 5.00 Very Low Very Low Very Low
American Trypanosomiasis 5 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low
Parasitic Infection 2 5.00 Very Low Very Low Very Low
Heart Disease 1 5.00 Very Low Very Low Very Low
Bites And Stings 1 5.00 Very Low Very Low Very Low
Parasitemia 1 5.00 Very Low Very Low Very Low
Body Weight 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Also, we have previously demonstrated that WRR-483 is a potent inhibitor of the cathepsin L-like cysteine protease, EhCP1, of E. histolytica, and is much more effective against EhCP1 than K11777. [39] Thus, it is possible that WRR-483 is targeting an as yet unidentified cathepsin L-like cysteine protease in T. cruzi as well.
WRR-483 Positive_regulation (targeting) of cathepsin L-like
1) Confidence 0.00 Published 2010 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2939063 Disease Relevance 0 Pain Relevance 0.03

General Comments

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