INT331595

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Context Info
Confidence 0.28
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.66
Pain Relevance 0.71

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Tlr9) signal transduction (Tlr9) endoplasmic reticulum (Tlr9)
plasma membrane (Tlr9) intracellular (Tlr9) lysosome (Tlr9)
Anatomy Link Frequency
hepatocyte 2
Tlr9 (Mus musculus)
Pain Link Frequency Relevance Heat
Paracetamol 6 98.88 Very High Very High Very High
ischemia 10 93.80 High High
antagonist 1 89.92 High High
aspirin 1 88.64 High High
cytokine 17 65.76 Quite High
chemokine 6 64.96 Quite High
Inflammation 24 35.28 Quite Low
fibrosis 6 5.00 Very Low Very Low Very Low
alcohol 4 5.00 Very Low Very Low Very Low
Bile 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 10 100.00 Very High Very High Very High
Death 3 99.64 Very High Very High Very High
Injury 47 98.58 Very High Very High Very High
Nash(non-alcoholic Steatohepatitis) 2 95.96 Very High Very High Very High
Cv Unclassified Under Development 10 93.80 High High
Hepatotoxicity 4 85.04 High High
Hepatitis 3 82.44 Quite High
Reperfusion Injury 7 82.40 Quite High
Sepsis 2 57.96 Quite High
Urological Neuroanatomy 1 46.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In acetaminophen injury, acetaminophen treatment results in hepatocyte death and the free DNA released from apoptotic hepatocytes activates TLR9.
Positive_regulation (activates) of Localization (released) of TLR9 in hepatocyte associated with paracetamol, injury, apoptosis and death
1) Confidence 0.28 Published 2010 Journal Gastroenterology Research and Practice Section Body Doc Link PMC2939438 Disease Relevance 1.66 Pain Relevance 0.71

General Comments

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