INT331599

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Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.80
Pain Relevance 0.73

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Tlr9) endoplasmic reticulum (Tlr9) intracellular (Tlr9)
cytoplasm (Tlr9) signal transduction (Tlr9) extracellular space (Il6)
Anatomy Link Frequency
neutrophils 2
Tlr9 (Mus musculus)
Il6 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 17 94.24 High High
ischemia 10 90.40 High High
Inflammation 24 89.16 High High
fibrosis 6 64.88 Quite High
Paracetamol 6 56.76 Quite High
chemokine 6 53.32 Quite High
aspirin 1 41.36 Quite Low
antagonist 1 40.88 Quite Low
alcohol 4 5.00 Very Low Very Low Very Low
Bile 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 47 99.40 Very High Very High Very High
Hepatotoxicity 4 93.56 High High
Reperfusion Injury 7 91.16 High High
Cv Unclassified Under Development 10 90.40 High High
INFLAMMATION 26 89.16 High High
Obesity 1 69.52 Quite High
Cirrhosis 25 65.36 Quite High
Urological Neuroanatomy 1 62.52 Quite High
Apoptosis 10 41.60 Quite Low
Death 3 40.80 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Injury in wt mice partly depends on TLR9 signaling in neutrophils, which enhanced production of ROS, IL-6, and TNF-?.
TLR9 Positive_regulation (enhanced) of Gene_expression (production) of IL-6 in neutrophils associated with injury
1) Confidence 0.03 Published 2010 Journal Gastroenterology Research and Practice Section Body Doc Link PMC2939438 Disease Relevance 1.80 Pain Relevance 0.73

General Comments

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