INT331602

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Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.90
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (SSRP1, Tlr4) nucleoplasm (SSRP1) signal transduction (Tlr4)
chromosome (SSRP1) plasma membrane (Tlr4) intracellular (Tlr4)
SSRP1 (Homo sapiens)
Tlr4 (Mus musculus)
Pain Link Frequency Relevance Heat
Bile 3 63.92 Quite High
Paracetamol 6 60.64 Quite High
cytokine 17 58.84 Quite High
ischemia 10 58.40 Quite High
fibrosis 6 52.56 Quite High
Inflammation 24 47.56 Quite Low
tolerance 1 7.80 Low Low
chemokine 6 5.00 Very Low Very Low Very Low
alcohol 4 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 47 98.08 Very High Very High Very High
Infection 7 72.72 Quite High
Hepatitis C Virus Infection 8 71.76 Quite High
Hepatitis B Virus Infection 1 71.36 Quite High
Hepatitis 3 64.80 Quite High
Fibrosis 9 61.32 Quite High
Toxicity 1 59.52 Quite High
Cirrhosis 25 59.48 Quite High
Cv Unclassified Under Development 10 58.40 Quite High
Reperfusion Injury 7 57.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, dying cells release RNA, which can engage TLR3; nuclear DNA that can engage TLR9; and HMBG1 (high mobility group box protein 1) that can engage TLR4.
high mobility group box Binding (engage) of TLR4
1) Confidence 0.03 Published 2010 Journal Gastroenterology Research and Practice Section Body Doc Link PMC2939438 Disease Relevance 0.90 Pain Relevance 0.21

General Comments

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